Our Group

Prof. Dr. Tiago Fleming Outeiro
Principal Investigator

Our research interests are focused on the understanding of the molecular mechanisms which lead to neurodegeneration in diseases such as Parkinson’s, Huntington’s, or Alzheimer’s disease. These diseases are intimately associated with protein misfolding and aggregation in specific regions of the brain.
Because the molecular pathways involved in protein homeostasis are highly conserved, we employ a wide variety of model organisms, from the simple but powerful budding yeast to mammalian cell culture and mice, to study the origin of the problems.
Our ultimate goals are to develop novel therapeutic approaches for these and other related disorders. We are working closely together with clinicians in order to accelerate drug discovery efforts, translating basic research into clinical applications that will improve the lives of patients.

  • touteir(at)gwdg.de

  • 49+ 551 39 67951

  • 49+ 551 39 67949

Sonja Reisenauer
Personal Assistant Prof. Outeiro

  • sreisen(at)gwdg.de

  • 49+ 551 39 67950

  • 49+ 551 39 67949

Postdoctoral Fellows

Dr. Ellen Gerhardt
Postdoctoral Fellow

  • egerhar1(at)gwdg.de

Dr. Mohammed Al-Azzani
Postdoctoral Fellow

  • mohammed.alazzani(at)med.uni-goettingen.de

Dr. Manuel Flores León
Postdoctoral Fellow

  • manuel.floresleon(at)med.uni-goettingen.de

In my postdoctoral research project, I use cellular models that mimic the reduced activity of a key enzyme involved in lipid metabolism and lysosomal degradation pathway, as well as some mutants, to unravel the role of lipidostasis in aging and synucleinopathies.

Dr. Valentina Grande
Postdoctoral Fellow

  • valentina.grande(at)med.uni-goettingen.de

Dr. Tamer Abdelaal
Postdoctoral Fellow

  • tamer.abdelaal(at)med.uni-goettingen.de

My research focuses on mitochondrial dynamics, with a particular emphasis on the processes of fission and fusion that regulate mitochondrial shape, distribution, and function. By investigating the role of mitochondrial dynamics in the context of neurodegenerative diseases, our work aims to uncover how dysregulation in these mechanisms contributes to neuronal dysfunction and degeneration, offering potential avenues for therapeutic intervention.

PhD Students

Hebatallah Abdelrasol
PhD Student

  • hebatallah.abdelrasol(at)med.uni-goettingen.de

My main PhD work is about investigating the effects of alpha-synuclein aggregation (a neuronal protein that is linked genetically and neuropathologically to Parkinson’s disease) on the physiology  of neuronal population derived from human-induced pluripotent stem cells (hiPSCs).

Madiha Merghani
PhD Student

  • madiha.merghani(at)stud.uni-goettingen.de

I am interested in understanding the role of LRRK2 in the autophagy process.

Dawei Wang
PhD Student

  • dawei.wang(at)stud.uni-goettingen.de

Technical Staff

Daniela Proto
IT-Coordinator

  • dproto(at)gwdg.de

Christiane Fahlbusch
Technician

  • cfahlbu4(at)gwdg.de